ABSTRACT
The study included 62 women. They were divided into 2 groups. The first group consisted of 42 cases, who presented with perimenopausal bleeding, of whom 10 cases were previously histologically proven to have endometrial adenocarcinoma. The second group included 20 cases [10 cases premenopausal and other 10 cases were postmenopausal women] who had no complain and taken as control. All patients were subjected to full history taken, general, abdominal and local physical examination, transvaginal sonography and Doppler velocimetry of uterine artery were done one day prior to endometrial curettage for evaluation of endometrial thickness and RI of uterine artery. This study revealed that 71.7% of patients with abnormal endometrium [80% of cancer group and 68.8% of benign group] were found to have low RI of uterine artery. The lowest mean uterine artery RI was obtained in patient with endometrial carcinoma [mean RI = SE = 0.76 +/- 0.016 P <0.001]. Combination of endometrial thickness with RI of uterine artery by EVS and Doppler increase efficacy for detection of endometrial abnormalities up to 76.2%. UGP can detect about 80% of cases with endometrial carcinoma, while no change was obtained regarding the false positive result of UGP in endometrial hyperplasis. UGP could not differentiate between hyperplasia with or without atypis