ABSTRACT
@#Human Immunodeficiency Virus (HIV) infection severely affects the immune status of the infected person. This is a slow process, which, apart from the acute HIV illness in some, does not affect the infected person’s health in the early stages of the disease. As the disease progresses to a more advanced stage, many of the common infections begin to appear at a higher frequency, and for prolonged durations. As the immune deficiency advances further, it predisposes the person to a variety of life threatening cancers and opportunistic infections, otherwise rare in a healthy person. Clinical manifestation of any of these conditions marks the state of the infected person as a case of full blown AIDS. This includes many types of leukaemia and lymphomas. The first reported case of plasmablastic lymphoma (PBL) in Fiji in an HIV seropositive person is reported here.