ABSTRACT
Chronic liver disease [CLD] is an important condition, diagnosed mainly by liver biopsy and is a leading cause of death among the working class group. It is a major burden in sub-Saharan Africa where it leads to hepatocellular carcinoma with a high mortality. This study was a retrospective one undertaken to determine the safety of performing liver biopsy procedure between January 2000 to January 2009 in terms of the frequency of indications and side effects. A total of 279 entries were found out of which 270 [96.77%] had a definitive liver biopsy histology result. The main indication for liver biopsy was chronic viral hepatitis in 150 patients [53.76%] while the commonest complication was the post-procedure pain that was seen in 16 patients [5.7%]. The average duration of hospital stay after biopsy was 6.08 +/- 0.52 hours