Oxytocin and syntometrine in prevention of postpartum hemorrhage

To compare the effect and side-effects of intramuscular syntometrine and syntocinon in the management of the third stage of labor. Five hundred eighty-three women with a singleton pregnancy and normal vaginal delivery were randomly allocated to receive syntometrine [n=293] or oxytocin [n=290] at Queen Alia Military Hospital between 1° February 30th April 1997. The rate of postpartum hemorrhage and side effects of syntometrine and oxytocin in the two groups were statistically compared using chi-square test. No statistical significant difference was found between both groups, for postpartum hemorrhage at the end of 2nd and 3rd stage of labour. However, there were significant statistical differences in the incidence of side effects [Nausea, vomiting, hypertension] at the end of 2nd and 3rd stage of labor between both groups. Intramuscular Oxytocin is equally effective to intramuscular syntometrine in prevention of post-partum hemorrhage, but carried less side effects and complication in comparison to intramuscular syntometrine

impact of parity on obstetric and neonatal outcome

This study was carried out to evaluate the obstetric and perinatal outcome of grandmultiparous women, and to compare it to that of nongrandmultiparous women. Between January 1993 and June 1994, there were 10223 deliveries of twenty eight weeks and more at Prince Rashed Ben AI-Hassan Hospital, of which 2201 were to grandmultiparous women. The pregnancy out-come of both grandmultiparous and nongrandmultiparous women were compared and analyzed. The comparison of grandmultiparous women with the nongrandmultiparous, revealed no significant differences in the incidence of instrumental deliveries, ante- and post partum hemorrhage, malpresentations, diabetes, hypertension, fetal distress, neonatal deaths and stillbirths. Cesarean section rate, congenital malformations, multiple pregnancies and anemia were more common in grandmultiparous women than in the other group. Prolonged labor, preeclampsia and eclampsia, low birth weight babies and premature babies were more common in nongrandmultiparous women with significant statistical differences. Conclusions: Grandmultipara is not a major risk factor and it does not carry an increased risk of obstetric and perinatal mortality and morbidity