Neurosarcoidosis as a first presentation of systemic sarcoidosis: case report

Neurosarcoidosis [NS] is a well-recognized complication of systemic sarcoidosis, but it is an uncommon first presentation of the disease. Moreover, seizure disorder is a much less common presentation of this subset. We report a case of a 30-year-old male admitted with status epilepticus due to NS. Magnetic resonance imaging [MRI] of the brain demonstrated multiple nodular lesions. Chest radiograph showed bilateral hilar lymphadenopathy that proved by histopathological examination to contain non-caseating granulomas [NCG]. Other causes of granulomatous lesions were excluded by relevant investigations. Corticosteroids [CS] markedly improved the clinical and radiological findings. Seizures were well controlled by antiepileptic drugs