ABSTRACT
To investigate diagnostic value of ischemia-modified albumin [IMA] levels in patients applying to emergency with symptoms of acute coronary syndrome [ACS] and acute ischemic stroke [AIS]. Two patient groups [ACS and AIS] and a control group were constituted. The study was discontinued upon reaching 30 patients in each group. Following patient approval at the initial visit, a total of 10 ml venous blood sample was obtained from all patients with a high clinical suspicion of ACS and AIS. The Troponin I and the IMA levels were determined in the blood samples. Statistically significant higher IMA values were determined in the patient groups compared to the control group [p < 0.001 for both groups]. No statistically significant correlation was found between the IMA and the Troponin I values in the ACS and the AIS groups [p>0.05 for both groups]. The sensitivity of IMA was 83% and 87% for ACS and AIS, respectively. The specificity of IMA was 90% and 87% for ACS and AIS, respectively. The sensitivity and specificity values, determined according to the optimal cut-off values in the groups demonstrated that IMA could be a useful diagnostic marker in ACS and AIS patients