ABSTRACT
The hypnotic activity of diazepam was compared with that of inactive placebo in a double- blind, randomized study in 40 surgical patients the night before their scheduled procedures. Diazepam per os (10mg) produces a pattern of response that differed markedly from that of the placebo. The patient receiving diazepam fell asleep sooner, slept more soundly and steadily and more felt they had been helped to sleep, while fewer awoke during the night. The significant difference Was obtained in both hypnotic and ataractic effects between diazepam and inactive placebo. Neither diaxepam nor inactive placbo caused marked changes in vital signs or any serious side effects.
Subject(s)
Humans , Diazepam , Vital SignsABSTRACT
A fall in systemic arterial pressure after implantation of acrylic cement into the acetabulum and proximal femoral shaft in the surgery of total hip prosthesis was observed and also the following results were obtained in three cases of total hip prosthesis under general anesthesia. 1) Blood pressure was usually decreased immediately after implantation of acrylic cement and returned to normal level approximately within 5 minutes. 2) The marked fall in blood pressure was more often observed with the introduction of bone cement into the proximal femoral shaft but less with the acetabular implantation of bone cement. 3) It is urged to measure blood pressureat the minute interval immediately after insertion of bone cement.
Subject(s)
Acetabulum , Anesthesia, General , Arterial Pressure , Blood Pressure , Hip ProsthesisABSTRACT
The influence of the intravenous injection of single-dose diazepam on plasma potassium, sodium and chloride concentions was studied in 36 healthy patients undergoing minor surgical operations and this investigation was limited to the first 10 minutes after the intravenous injection of diazepam, 10mg. A significant decrease of plasma potassium concentration(-0.24 ~ -0.25 mEq/1) was observed with diazepam at 5 and 10 minutes but the diazepam investigated in this study did not have a significant effect on the plasma sodium and chloride.
Subject(s)
Humans , Diazepam , Injections, Intravenous , Plasma , Potassium , SodiumABSTRACT
Cardiac arrest is an alarming emergency. To be faced with it during strabismus surgery is a frightening experience for both surgeon and anesthesiologist. We have experienced with a case of cardiac arrest during traction of medial rectus muscle for strabismus surgery. Surgery was completed successfully after retrobulbar block with 2% lidocaine.