ABSTRACT
For the establishment of the association of the chronic fungal infection with cell mediated immunity, delayed cutaneous hypersensitivity was measured for 96 patients with chronic dermatophytosis and 40 healthy adults by means of Multitest CMI. The patient group increased in rates of positivity to candida, trichophyton and diphtheria, but decreased in rates of positivity to proteus, streptococcus and tuherculin. The rate of positivity of the patient group in the antigen of trichophyton(14%) was shown as higher than that of the control group(8%). A big difference in the sum of diameters was shown between patients with nail infection(22.5+/- 113mm for male, 16.3+8.93mm for female) and patients without nail infection(17.8+/- 7.62rnm for male, 11.44.37mm for female). In conclusion, in the present study, the difference in the delayed cutaneous hypersensitivity between patient group and control group is not provided. Even though the possibility of defect of cell mediated immunity in chronic dermatophytosis is admitted, there are some doubts regarding the Multitest CMI being the adequate method ta check the state of cell mediated immunity of individuals who have trivial or partial defect in immunity.
Subject(s)
Adult , Humans , Male , Candida , Diphtheria , Hypersensitivity , Immunity, Cellular , Proteus , Streptococcus , Tinea , TrichophytonABSTRACT
Fournier's gangrene is a fulminating gangrene of the male genitalia. It is associated with severe systemic toxic effect and a high motality rate, and it requires early diagnosis and intensive care with surgical intervention. We report a case of Fournier's gangrene in 33-year-old man, who showed marked swelling and necrosis of the scrotum, and extending cellulitis on the right flank and chest. With prompt excision of all the gangrenous scrotal skin and drainage incisions made on the flank and chest, the healing was successful.
Subject(s)
Adult , Humans , Male , Cellulitis , Drainage , Early Diagnosis , Fournier Gangrene , Gangrene , Genitalia, Male , Critical Care , Necrosis , Scrotum , Skin , ThoraxABSTRACT
The coexistence of the variants of porokeratosis is very rare. We report a case of coexistence of linear porokeratosis with disseminated superficial actinic porokeratosis (DSAP). A 43-year-old wornan first noticed a brownish papule on the left side of groin in early infancy. She developed multiple discrete or confluent keratotic plaques in linear fashion on the left lower extrernity and trunk in childhood. These leaions became pruritic in summer. Two years ago, she developed multiple scattered small annular lesions on the face and forearms. Her family history showed no abnormalities. Biopsy specimene from the groin and trunk showed eornoid lamella.