ABSTRACT
Background: Stress hyperglycemia among patients having an acute pathology is frequently described in recent studies
Aims: The objectives of this work were to describe epidemiologic features of elderly patients hospitalized in the emergency department and having a hyperglycemia due to stress
Methods: A retrospective chart review identified patients older than 65 years with obtained serum glucose levels. Patients with diabetes were excluded. Two levels of serum glucose were considered [>6,9 mmol/l and
Results: We included 165. There were 94 patients with high level of serum glucose level [56,9%]. Multivariate analysis found that only cardio-vascular pathologies were more predictive of having stress hyperglycemia [p=0,014, odds-ratio=2,8, IC=1,2-6,4]. There were no correlation between serum glucose levels and mortality
Conclusion: Stress hyperglycemia is a fairly common disorder but underestimated in emergency department. Its impact on the prognosis of elderly patients remains to be studied
ABSTRACT
Mental retardation [MR] is a group of heterogeneous clinical conditions. There are more than 900 genetic disorders associated with MR and it affects around 3%of the general population. Many MR conditions described are syndromic, fragile X syndrome being the most common clinical entity among them. Xlinked mental retardation [XLMR] is subdivided in two categories: syndromic XLMR [MRXS] when MR is associated with clinical features and non-syndromic XLMR [MRX] when MR is isolated. The aim of this systematic review of the literature was to join together the results of several studies related to X linked mental retardation and to present various genes implicated in this disease. In this review, focus has been given on genes implicated in mental retardation, the clinical data and on phenotype-genotype correlations. An exhaustive electronic and library research of the recent literature was carried out on the Web sites "Science Direct" and "Interscience Wiley". The key words used were "mental retardation", "X chromosome", "gene", "syndromic mental retardation", "non-syndromic mental retardation". In this review a number of X linked genes, the clinical features associated with the gene abnormality, and the prevalence of the disease gene are discussed. We classified these genes by order of their first implication in MR. A table presented on the XLMR Update Web site who list the 82 known XLMR genes is available as XLMR Genes and corresponding proteins