Relation of body mass index with lipid profile and blood pressure in young healthy students at Ziauddin medical university

This study was conducted to assess serum lipids in healthy young subjects in relation with their BMI. Students of Ziauddin Medical University were assessed for anthropometric measures, blood pressure and lipid profile at the time of their admission for MBBS program. Out of 426 students all parameters were available for 301 students and they were selected for analysis in this study. Mean serum cholesterol in 301students was 149.3 +/- 31.3 mg/dl, mean LDL-C was 91.3 mg/dl +/- 27.7, mean HDL-C was 40.0 mg/dl +/- 42.2, mean triglycerides were 89.9 mg/dl +/- 42.2, mean systolic blood pressure was 113.1 mmHg +/- 13.5 and mean diastolic blood pressure was 74.0 mmHg +/- 8.1. The mean BMI of students was 21.6 Kg/m2 +/- 4.2. Among 301 students, 88 were underweight, 175 were normal and 38 were overweight according to their BMI. We found no significant difference in mean serum cholesterol and LDL-C while there were significant difference in mean serum HDL-C, triglycerides, systolic and diastolic blood pressure among the three BMI groups. In our study, there are high numbers of at-risk individuals. Therefore, strategies should be designed for weight reduction in children and adults to prevent cardiovascular disease

Comparison of troponin T and enzyme levels in acute myocardial infarction and skeletal muscle injury

The objective of this study was to compare the levels of troponin T and enzymes levels in myocardial infarction and skeletal muscle injury. This study was carried out at Basic Medical Sciences Institute, JPMC Karachi, Pakistan. Ninety subjects were selected. Thirty controls, thirty patients suffering from myocardial infarction and thirty suffering from skeletal muscle injury were selected from National Institute of Cardiovascular Diseases. Creatine kinase, aspartate amino-transferase, lactate dehydrogenase and Troponin T were determined by kit methods. Troponin T level rises significantly [p<0.01] in patients suffering from myocardial infarction. Creatine kinase [CK], CKMB, aspartate aminotransferase and lactate dehydrogenase levels rises significantly [p<0.01] in both groups compared with controls. Troponin T is an early indicator of myocardial infarction and is superior to CKMB in diagnosis of myocardial injury. There is no increase in troponin T levels in skeletal muscle injury