The Review of Cervical Conization For Twelve Years / 대한산부인과학회지

OBJECTIVE: The purpose of this study is to evaluate the role of cold knife conization in the diagnosis and management of cervical neoplasia. METHODS: Cold knife conization was performed in total 163 patients from January 1992 to December 2003. The results of PAP smear and colposcopy-directed biopsy were compared with the pathologic diagnosis of conization. And we evaluated the rate of positive margin and the presence of residual lesion. And then, we reviewed the pregnancy outcome after conization. RESULTS: The rate of agreement between PAP cytology and conization was 45.4%, and the rate of agreement between colposcopy-directed biopsy and conization was 65.6%. Hysterectomy was done in 102 patients (62.6%). The positive rate of resection margin was 19.6%. The incidence of residual lesion after conization was 31.2% in margin (+) and 1.4% in margin (-). We evaluated 7 cases of pregnancy after conization. CONCLUSION: Cervical conization as surgical treatment was effective in cervical neoplasia patients, especially young patients, with continuous follow-up.

Prenatal sonographic diagnosis of fetal hepatic hemangioma / 대한산부인과학회지

Infantile hepatic hemangioma is benign vascular tumor and the most common liver tumor in infants. Small hepatic hemangioma is usually asymptomatic and seldom require therapy. Giant hepatic hemangioma, defined as more than 4 cm in diameter, is rare, but can lead to life-threatening complications such as consumptive coagulopathy, anemia, hemorrhage after tumor rupture and congestive heart failure due to arteriovenous shunting. Neonatal mortality rate is about 70-90%. The differential diagnosis of a fetal liver mass includes hemangioma, hepatoblastoma, and mesenchymal harmatoma. Although hepatic hemangioma represents the most common tumor of the liver in infant, the prenatal diagnosis of this condition has been rarely reported in the literature. we experienced a case of fetal hepatic hemangioma by prenatal sonography and report our case with a brief review of literature.

Primary Ovarian Pregnancy: A Case Report / 대한산부인과학회지

Primary ovarian pregnancy is rare form of ectopic pregnancy. It can be diagnosed if the only implantation occurs in the ovary. The clinical diagnosis of ovarian pregnancy is difficult. Owing to the availability of sensitive assays for human chorionic gonadotropin and the development of transvaginal ultrasonography, early diagnosis of an ectopic pregnancy has been made more feasible. But clinical and even intraoperative diagnosis of ovarian pregnancy is still difficult and only microscopic examination of tissue specimen can confirm the diagnosis. Misdiagnosis is common because it can be confused with a ruptured corpus luteum. Laparoscopic wedge resection is treatment of choice. The authors present a case of ovarian pregnancy with a brief review of the literatures.

A Successful Surrogate Pregnancy in a Patient with Mayer-Rokitansky-Kuster-Hauser Syndrome / 대한산부인과학회지

Lack of mullerian development (Mayer-Rokitansky-Kuster-Hauser Syndrome) is characterized by absence of apparent vagina and/or uterus, normal secondary sexual characteristics, normal reproductive hormonal profile, and a relatively common cause of primary amenorrhea about 1 in 4,000 female births and also cause of primary infertility. Management for these women comprise of construction of neovagina for sexual life. In 1985, the first report of a successful pregnancy through the uterine surrogacy was made. It is being possible for these women to have new opportunity of getting her own genetic offspring. Since ovarian activity is completely preserved in patients, controlled ovarian hyperstimulation is similar to any other IVF case that is with urinary or recombinant gonadotropins following GnRH agonist down regulation. Genetic offspring can be achieved by cellection of oocytes from the genetic mather, in-vitro-fertilization by the genetic father, and placement into a surrogate carrier. We have experienced a case of successful surrogate pregnancy in a patient with congenital absence of vagina and uterus.