ABSTRACT
In 1982, we reported a case of recalcitrant urethritis caused by a strain of spectinomycin resistant PPNG. It caused a great fear that it might be the signal of an end of spectinomycin era, The disk-prediffusion method was used on all isolates from the Choong-Ku VD Clinic between August 1984 and December 1985 to screen out strains of N. gonorrhoeize resistant to spectinomycin, with disks containing 100pg of spectinomycin, Strains with inhibition zone greater tha.n 25 mm were considered susceptible, We could not disclose a single strain which wa.s resistant to spectinornycin, The reason why we do not see any more of spectinomycin. N. gonorrhoeae requires some speculation, It is possible that the mutant which had resistant to spectinornycin might not have teen quite stable and, after series of passage through human hosts, mutated back to original spectinornycin sensitive states. It is suggested that continual surveillance for spectinomycin resistant N. gonorrhoeae should be conducted.
Subject(s)
Adolescent , Humans , Neisseria gonorrhoeae , Neisseria , Spectinomycin , UrethritisABSTRACT
The treatment of gonorrhea caused by beta-strains of N. gonorrhoeae is quite different from that of non-beta-strains, but it is not always possible in general practice to take cultures of gonococci to detect p-lactamase producing organisms. Therefore treatment regimens commonly used for gonorrhoea should be effective against both PPNG non-PPNG strains. Eighty-seven male uncomplicated gonorrheal patients were treated with intramuscular kanarnycin 2gm in combilnation with talampicillin 2. 5 gm plus probenecid 1grn orally. Sixty-seven patients were followed up. All patients recovered. Ten patients among sixty-seven patients had PPNG. A regimen of intramuscular kanamycin 2 gm, talampicillin 2. 5 gm plus probenecid 1 0 gm orally seems to be one of the most cost effective regimens in Korea.
Subject(s)
Humans , Male , General Practice , Gonorrhea , Kanamycin , Korea , Probenecid , TalampicillinABSTRACT
Urethral duplication is rare congenital anomaly. It may be complete or partial, We report a case of PPNG urethritis which limited to the accessory urethra and treated with kanamycin (2. 0gm, im), ampicillin(3. 5gm, po) and probenecid(l pgm, po).
Subject(s)
Kanamycin , Urethra , UrethritisABSTRACT
Erythromelanosis follicularis faciei et coli is a pigmentary disorder of unknown cause originally described by Kitamura et al in 1960. We describe two cases of erythromelanosis follicularis faciei et colli occured in adolescence. Clinical features of these patients were consistent with the clinical changes described in previous cases having clinical triad of erythema, hyperpigmentation and follicular papules. This pigmentary disorder may not be an uncommon disease, however it might be neglected from the concern of the dermatologists.