ABSTRACT
Spinal epidermoid are rare lesion of spine. We report a case of 12 year old female who presented with difficulty in walking and weakness in left lower limb. MRI spine showed epidermoid at level of L1-L2. Laminectomy and surgical excision of the cystic lesion was planned .Intra operativelya pearly white tumor adherent to cord was found and excised. Histopathological examination confirmed the diagnosis of epidermoid cyst. One year after surgery she again came with complaint of pain at the site of surgery following which MRI was done which showed recurrence of epidermoid, intra operatively it was found that it was a cystic cavity filled with hemolyzed blood mimicking as recurrent epidermoid radiologically
ABSTRACT
Synovial Sarcoma is a soft tissue neoplasm having incidence 6%- 10%.Malignant cells in synovial fluid aspiration is extremely rare. Only 5%cases have been reported to have joint cavity involvement. We report a case of synovial fluid malignant effusion of knee joint in a 35 year old male who presented with a left popliteal fossa swelling. Synovial fluid aspiration revealed tumor cell clusters with anaplastic morphology .Subsequent biopsy showed spindle cell tumor consistent with synovial sarcoma. This is a rare presentation of synovial sarcoma with the presence of malignant cells in synovial fluid
ABSTRACT
Oral cancer is one of the leading cause of cancer in India, new diagnostic modalities for early diagnosis and treatment will increase the survival of the patients. The present study was carried out with an aim to evaluate salivary levels of EGFR in oral cancer and pre-cancer as tumor marker. For this purpose an observational case-control study was carried out in which a total of 72 subjects were enrolled.Of these 24 (33.3%) were patients of premalignant oral lesions and 24 (33.3%) were patients of malignant oral lesions& 24 (33.3%) subjects were normal healthy controls. Demographic information and clinical data was obtained, estimation for EGFR was performed in saliva. In premalignant cases, buccal mucosa was the most common site involved (87.50%) whereas in malignant cases tongue was the most common site involved (n=10;41.67%). Mean salivary EGFR levels were higher in malignant cases (0.23±0.17 pg/ml) and low in controls (0.10±0.19 pg/ml). Mean EGFR levels in premalignant cases were 0.12±0.22 pg/ml. statistically, this difference was not significant (p=0.052). Statistically, no significant difference in mean EGFR levels among different TNM stages could be seen (p=0.145). EGFR levels showed a potential to discriminate between malignant and premalignanat cases but this difference was statistical insignificant due to lower sample size.
ABSTRACT
Walthard cell rests are benign cluster of epithelial cells found in connective tissue of fallopian tubes and also seen in the mesovarium, mesosalpinx and ovarian hilus. It was proposed that Walthard cell rests may be a source of Brenner's tumor or primary urothelial cell carcinoma because of similar histogenetic origin of their cells. Here we report a case which not only during gross examination showed peculiar peritubal glistening tiny nodules but also demonstrated attention grabbing clusters of cell on histopathology, mimicking ? A tumor. A diagnosis of Walthard cell rest was made. One should always consider a differential diagnosis as Brenner's tumor (primary) or serosal implant from gynaecological, genitourinary or other tumors before making a confirmatory diagnosis of Walthard cell rest.