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1.
Asian Pacific Journal of Tropical Biomedicine ; (12): 739-749, 2017.
Article in Chinese | WPRIM | ID: wpr-950549

ABSTRACT

Objective To establish the chemical profile, and to evaluate the antibacterial and modulatory activity of the ethanolic extracts of the stalk's inner bark and heartwood of Secondatia floribunda. Methods Quantification of total phenols and flavonoids was determined by the Folin-Ciocalteu method and aluminum chloride, respectively. Phenolic compounds were identified and quantified by HPLC-DAD (High Performance Liquid Chromatography-Diodearray Detector) and the Infrared Spectroscopy was performed using the measure by Attenuated Total Reflectance with Fourier Transform (ATR-FTIR). Antibacterial assays for determination of the Minimum Inhibitory Concentration (MIC) and modification of aminoglycosides were performed by microdilution. Results Infrared spectra showed similar characteristics, having among its main absorption bands hydroxyl group (OH). The antibacterial activity showed clinically significant results for the strains of Staphylococcus aureus and Escherichia coli. In modulation assay, synergic and antagonistic effect for both extracts was observed. Heartwood extract in combination with antibiotics showed a significant MIC reduction at 19.8% (P < 0.000 1)-79.3% (P < 0.01). Conclusions This study is the first report of chemical and biological information of Secondatia floribunda suggesting that it is clinically relevant source of a new antibacterial therapy, especially due to the presence of significant levels of phenolic compounds.

2.
Rev Rene (Online) ; 13(3): 659-666, 2012.
Article in Portuguese | LILACS, BDENF | ID: lil-693915

ABSTRACT

nvestiga o saber popular sobre o uso de plantas medicinais no tratamento de doenças respiratórias na infância. Estudo descritivo exploratório de natureza qualitativa, realizado em Juazeiro do Norte/CE com vinte e duas mães e/ou responsáveis de crianças usuárias da Estratégia Saúde da Família. A coleta de dados foi efetuada entre os meses de junho e julho de 2011 através de entrevista semiestruturada. Empregou-se a técnica do Discurso do Sujeito Coletivo para análise de dados. A pesquisa indicou que o saber popular tem grande significado e é amplamente aceito, sendo utilizado em algumas vezes em substituição aos medicamentos sintéticos. Ressaltou ainda, a relevância da transmissão cultural deste saber por gerações. Acreditamos na importância de que os profissionais da saúde discutam as práticas populares de saúde para que possam atuar de forma mais efetiva na resolução dos reais problemas de saúde, aliando o conhecimento popular ao científico e fortalecendo tais práticas.


Subject(s)
Humans , Child , Respiratory Tract Diseases , Medicine, Traditional , Plants, Medicinal , Child Health
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