Transurethral microwave thermotherapy versus sham treatment: early report of a randomized double-blind study

Transurethral microwave thermotherapy [TUMT] for the management of clinical BPH has recently been introduced and investigated in a number of centres. A prospective double-blind randomized study was designed to evaluate the extent of any placebo response. The inclusion criteria were a total Madsen score > 8, a Qmax

Use of glutaraldehyde cross-linked collagen for treatment of urinary incontinence

Stress urinary incontinence was treated by multiple modalities but remains a problem. Injectable materials have been used to augment the urethral sphincter and improve urinary continence with some success. The present study investigated the efficacy and safety of periurethral injection of glutaraldehyde cross-linked collagen for treating stress urinary incontinence. 21 female patients were treated, all of them had previous surgery for incontinence. Most of the patients were type 1 and 2 incontinence. Before and after the implantation all patients underwent urodynamic evaluation. The glutaraldehyde cross-linked collagen was injected into the area of bladder neck or urinary sphincter under direct endoscopic control. The number of injections ranged between 1 and 3, and the average volume of collagen used was 8.2 ml. The mean follow up period was 8.3 months. 11 [52%] patients were cured, 8 [38%] improved and 2 patients were unchanged and proceeded to surgery. No complications were reported. The results demonstrated that periurethral collagen injection is safe and simple to be performed, so as to correct stress urinary incontinence in females