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1.
Tunisie Medicale [La]. 1995; 73 (2): 109-117
in French | IMEMR | ID: emr-39886

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5.
Tunisie Medicale [La]. 1988; 66 (1): 5-12
in French | IMEMR | ID: emr-11816

ABSTRACT

The monoclonal antibodies are immunoglobuliuns having the same isotypic. allotypic and idiotypic characteristics They are specific for one antigenic determinant. By fusion of immunocompetent B lymphocyte with a myelomatous cell, Koehler and Milstein managed to immortalise a hybrid cell able to produce the monoclonal antibodies By their elevated specificity and perfect reproducibility, Monoclonal antibodies present a precious instrument for medicine and fundamental research. We present in this review a survey of obtention and utilisations of these antibodies

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