ABSTRACT
Chlamydia trachomatis is a common cause of sexually transmitted disease which can cause severe consequences. Appropriate preventive requires knowledge of epidemiology of infection in different population in order to target interventions in a cost-effective manner. In this study prevalence of C. trachomatis infections were determined according to some parameter in Mashhad. In this study serum from 76 patients with STD were examined by ELISA and IFA for C. trachomatis. Statistical evaluation was done using SPSS program. ELISA showed that 11 and 3 patients with IgG and IgM against C. trachomatis, respectively. IFA analysis showed that 1 patient had titer of 1/32, 6 patients with 1/64 and 3 patients with 1/128. One female patient showed titer of 1/256. This study provides strong evidence that Chlamydia prevalence in our region is significantly high which necessitate screening and treatment. It is, therefore, suggested that detection test for chlamydial genito-urinary infections become a routine part of STD investigations