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LMJ-Lebanese Medical Journal. 2010; 58 (2): 71-75
in French, English | IMEMR | ID: emr-98200

ABSTRACT

To study the efficacy of surgery on the postoperative control of epilepsy in patients operated for brain tumors. Forty patients operated for supratentoriel cerebral tumors with epilepsy, at Hotel-Dieu de France [HDF] hospital center, between 1983 and 2005, were included in this study. Clinical, paraclinical and surgical information were collected. The extent of the tumor resection was based on the postoperative MRI results. The mean duration of the follow-up was 52 +/- 6 months [from 6 months to 10 years]. 62.5% of our patients have had acute seizures [<1 year] and 37% had experienced chronic seizures [>/= 1 year]. The histopathologic exam revealed 2 DNET, 3 pilocytic astrocytomas, 2 diffuse astrocytomas, 6 A oligodendrogliomas, 7 B oligodendrogliomas, 7 anaplastic astrocytomas and glioblastomas and 13 meningiomas. Twenty-two patients had a complete resection, whereas the postoperative MRI of 18 patients have shown a tumoral remnant. After one year of follow-up, a complete remission was noted in 57,5% of the patients [EngelI]. The prognostic factors of good outcome were: low-grade glial tumors [I +/- II], meningiomas, and complete tumor resection. The efficacy of surgery for epilepsy associated to cerebral tumors, established by the majority of articles, matched the results obtained for the patients operated at HDF, with complete seizures control in 57,5% of patients. This control depended essentially on the extent of tumor resection and on tumor's nature


Subject(s)
Humans , Child , Adolescent , Adult , Aged , Middle Aged , Male , Female , Brain Neoplasms/surgery , Brain Neoplasms/pathology , Prognosis , Treatment Outcome , Magnetic Resonance Imaging
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