Clinical Characteristics at Initial Diagnosis of Korean Patients with Retinitis Pigmentosa

Purpose@#To evaluate the clinical characteristics of Korean patients diagnosed with retinitis pigmentosa. @*Methods@#We retrospectively reviewed the medical records of patients diagnosed with retinitis pigmentosa from January 2014 to December 2019. We evaluated age, gender, the chief complaints, posterior subcapsular cataract status, abnormalities on optical coherence tomography, visual field test results, and electrooculograms. @*Results@#A total of 492 eyes of 246 patients were included. The mean patient age was 48.0 ± 16.0 years and the chief complaints were decreased vision and night blindness. The mean logarithm of the minimal angle of resolution (logMAR) best‐corrected visual acuity (BCVA) was 0.31 ± 0.50. The BCVA was 0.5 or better in 368 eyes (74.8%). A total of 328 (71.0%) of 462 eyes that underwent visual field testing exhibited visual field defects within 10º. The mean Arden ratio was 1.28 ± 0.28 for the 242 eyes that underwent electro‐oculography. Optical coherence tomography revealed vitreomacular traction/an epiretinal membrane, cystoid macular edema, and retinal thinning in 135 (27.4%), 48 (9.8%), and 112 (22.8%) eyes, respectively. The ellipsoid zone was intact in 222 eyes (45.1%), disrupted in 220 (44.7%), and absent in 50 (10.2%). @*Conclusions@#Most patients with retinitis pigmentosa exhibited visual acuity of 0.5 or better, but also had central visual field defects. Various abnormalities were noted on optical coherence tomography of most patients.

Clinical Characteristics of Patients with Pinguecula between 20 and 39 Years of Age

PURPOSE: To describe the characteristics of patients with pinguecula between the ages of 20 and 39. METHODS: Thirty-two patients who visited our hospital between February 2013 and November 2013 for pinguecula were enrolled in the study. The clinical characteristics were evaluated by the location, size, shape, elevation, color, vascularization and the grade of pingueculae. RESULTS: Ninety-eight pingueculae were found in the 32 patients, 58 (59.18%) pingueculae on the nasal side, and 40 (40.82%) pingueculae on the temporal side. The mean grade of pingueculae of the nasal side was 1.19 +/- 0.40 and on the temporal side was 1.15 +/- 0.43. Compared with the temporal side, pingueculae on the nasal side were more frequent (p = 0.032). The size, color, shape and vascularization of nasal and temporal pingueculae were not significantly differentiated. Medical history, tear film break-up time, Schirmer test, history of contact lens wearing, refractive surgery, occupational activity and residence were not correlated with the grade of pingueculae. However, ocular surface disease index score was correlated with the grade of nasal pingueculae (p = 0.01). CONCLUSIONS: The pingueculae of the nasal side were more frequent than of the temporal side in patients between 20 and 39 years of age, and dry eye disease with tear film instability was also present. The ocular surface disease index score increased with the grade of nasal pingueculae.

Treatment of Recurrent Conjunctival Papilloma with Topical Mitomycin C

PURPOSE: To provide a case report of 1 patient (1 eye) who experienced recurrences of conjunctival papilloma and was treated with complete resection, electrocauterization, cryotherapy, intraoperative application of mitomycin C and postoperative topical mitomycin C. CASE SUMMARY: We evaluated the clinical course of a 42-year-old male with recurrent conjunctival papillomas on the left upper and lower tarsal conjunctiva who was treated 10 times with a simple resection over the past 8 years. The patient was treated with complete resection, electrocauterization, intraoperative application of mitomycin C and cryotherapy. Topical mitomycin C was applied for 1 month. There was no recurrence or complications for 12 months postoperatively. CONCLUSIONS: Complete resection, electrocauterization, intraoperative application of mitomycin C, cryotherapy and topical mitomycin C in patients with recurrent conjunctival papilloma was shown to be an effective treatment without recurrence and complications.

Treatment of Recurrent Conjunctival Papilloma with Topical Mitomycin C

PURPOSE: To provide a case report of 1 patient (1 eye) who experienced recurrences of conjunctival papilloma and was treated with complete resection, electrocauterization, cryotherapy, intraoperative application of mitomycin C and postoperative topical mitomycin C. CASE SUMMARY: We evaluated the clinical course of a 42-year-old male with recurrent conjunctival papillomas on the left upper and lower tarsal conjunctiva who was treated 10 times with a simple resection over the past 8 years. The patient was treated with complete resection, electrocauterization, intraoperative application of mitomycin C and cryotherapy. Topical mitomycin C was applied for 1 month. There was no recurrence or complications for 12 months postoperatively. CONCLUSIONS: Complete resection, electrocauterization, intraoperative application of mitomycin C, cryotherapy and topical mitomycin C in patients with recurrent conjunctival papilloma was shown to be an effective treatment without recurrence and complications.