ABSTRACT
BACKGROUND: Patients with liver cirrhosis are regularly examined for the evaluation of esophageal varices. Those with large varices should be treated with beta-blockers. The aim of this study was to determine whether clinical variables were predictive of the presence of esophageal varices or high-grade varices. METHODS: The medical records of 257 patients, diagnosed as having liver cirrhosis and underwent esophagogastro-duodenoscopy (EGD), were reviewed. None had a history of malignancy and variceal hemorrhage before EGD. Clinical findings were analyzed in relation to the presence of esophageal varices and high grade esophageal varices. RESULTS: The multiple logistic regression analysis showed an independent association between the presence of esophageal varices and ascites and low platelet count. Only low platelet count showed association with high grade esophageal varices. The cut-off value of predictive model for high grade esophageal varices was 73,766/microliter and its sensitivity was 75%, specificity 65.7%, negative predictive value 96.2%, and positive predictive value 18.6%. CONCLUSION: Our analysis showed that low platelet count and ascites were independent predictive factors for esophageal varices. For high grade varices, the platelet count was the only predictive factor. Endoscopic screening for detection of high grade varix is highly recommended when the platelet count is lower than 74,000/microliter is observed in patients with liver cirrhosis.
Subject(s)
Humans , Ascites , Esophageal and Gastric Varices , Hemorrhage , Liver Cirrhosis , Liver , Logistic Models , Mass Screening , Medical Records , Platelet Count , Sensitivity and Specificity , Varicose VeinsABSTRACT
BACKGROUND: Falls in the elderly can lead to disability, hospitalizations, and premature death. Even if the fall does not cause significant injury, it may lead to fear of falling, loss of self confidence and restriction of ambulation. Thus, we conducted this study to examine the risk factors of falls in the elderly. METHODS: The study population consisted of 70 persons, older than 65 years. Subjocts were subdivided into 3 groups according to their experience of falls, during the past 2 year period. Among them, 30 persons had no previous experience, 20 had one fall, and 20 more than one fall. Age, past history, situations surrounding falls, MMSE K, GDS short form, ADL, IADL, Mini Nutritional assessment (MNA) were reviewed, and the Get up and go test, evaluation of orthostic hypotension and hearing were done. T-test, chi square, ANOVA, logistic regression test using the SAS program was performed. RESULTS: The mean age of the participants was 75.4 years with 62.9% malas. The factors associated with falling were age (P=0.01), scores of MNA (P=0.04), Get up and go test (P=0.004), past history (P=0.01), MMSE K (P=0.02), GDS short form (P=0.001), ADL (P=0.003) and IADL (P=0.002). Those in the group who fell once occured mostly while doing a riskful task, while those who fell more than once happened mostly during positional change (p<0.0001). Independent predictors of falls were get up and go test results and GDS short form scores. CONCLUSION: The independent predictors of falls were Get up and go test results and Geriatric Depression Scale scores.
Subject(s)
Aged , Humans , Activities of Daily Living , Depression , Hearing , Hospitalization , Hypotension , Logistic Models , Mortality, Premature , Nutrition Assessment , Risk Factors , WalkingABSTRACT
BACKGROUND: Recently Live blood analysis was populated in korean society. so we evaluated clinical utility of Live blood analysis, as compared the Live blood analysis result of patients who have confirmed diagnosis of disease with that of controls who have no known health problems. METHODS: We carried out Live blood analysis to patients(n=30) who was entered to an admission in Yongdong severance hospital from February 2000 to March 2000 and to controls(n=30) who worked in that hospital at same time. We examined 3 abnormal finding; rouleau formation, spicule, protoplast, which were often observed in Live blood analysis. RESULTS: At comparison of patient group and control group, rouleau formation was observed in 27 patients except 3 patients and it was observed in all 30 controls. Spicule was observed 2in 9 patients except 1 patients and it was observed in all 30 controls. Protoplast was observed in 16 patients and 13 controls. There was no difference between patients and controls in observing 3 abnormal finding. CONCLUSION: We conclude that Live blood analysis may have no clinical significance.