ABSTRACT
A total of 402 Iraqi patients diagnosed as Acute Lymphoblastic Leukaemia [ALL] over a four year period [1987-1990] were studied. T-ALL was identified in 143 cases of the above patients [35.57%] based on the characteristic acid phosphatase reaction - Such a relative frequency is much higher than any reported study from the West. T-ALL had a peak occurrence at 6-10Yr age group. While the Non T had its peak at 0-5Yr group, and the former included significantly more males than the latter[p0.05]. the application of the FAB morphological classification revealed that the T-ALL included a significantly higher number of cases with L2 morphology as compared to the non T[P<0.001], and no cases with L3 morphology. furthermore T-ALL had higher median haemoglobins [p0.001]. leucocytes [o<0.001]and peripheral blood proportion of plast [p<0.05]than the non T this study also included a discussion of the possible cases of the relatively high frequency of the T- cell type in Iraq ALL patients. and its various haematological and morphological association
Subject(s)
Humans , Leukemia-Lymphoma, Adult T-CellABSTRACT
Clinical, haematological and bone marrow histo!ogical patterns were studied in a series of 68 Iraqi patients with chronic lymphocytic Leukaemia. The application of the two major clinical staging systems [namely the Rai and Binet systems] to the classification of patients in this series showed that the majority had an advanced stage at presentation [63.2% were Binet stage C [Rai stages III and IV]], Bone marrow histological patterns were diffuse in 51.5%, mixed in 32.3% and interstitial in 16.2%, while none were nodular. Such findings are quite different. from those reported from North America and Europe, Where early and Intermediate clinical stages and interstitial marrow histological patterns predominate. Furthermore, significant correlations between the marrow histological patterns and both Rai and Binet staging systems were found, a finding which is consistent with studies from Western countries