ABSTRACT
Objective: To assess the diagnostic accuracy of CT scan in detecting paranasal sinus fungal infections
Study Design: Cross-sectional, observational study
Place and Duration of Study: Department of Radiology, Ziauddin University Hospital, Karachi, from April to September 2014
Methodology: Patients with clinical suspicion of fungal sinusitis were included in this study. Patients with already diagnosed or history of recurrent fungal infections were excluded. All these patients underwent CT scan examination of paranasal sinuses. Findings were recorded. Final diagnosis was based on smear analysis for fungal culture. Accuracy analysis was conducted for CT diagnosis using smear analysis as the gold standard. Kappa analysis was conducted to determine agreement
Results: Out of the 120 patients, 71 [59%] were male. The sensitivity, specificity, positive predictive value and negative predictive value of CT were 96.19%, 93.33%, 99.01%, 77.77%, respectively. The diagnostic accuracy was 95.83%. Kappa statistics showed 82% agreement beyond chance
Conclusion: CT scan is highly accurate in diagnosing and characterizing fungal infection of paranasal sinuses. It also determines the extent of disease which eventually aids in deciding the surgical approach to be used
ABSTRACT
Objective: To determine the diagnostic accuracy of Computed Tomography [CT] in patients with neck and mediastinal lymphoma and correlate with gold standard histopathology results. Period: This study was conducted during six months period extended from March 2013 to September 2013. Setting: Department of diagnostic radiology, Dr. Ziauddin University Hospital, Karachi
Methodology: A total of 366 patients presenting with sign and symptoms such as fever, night sweats, weight loss or having any swelling in the cervical region were included and CT was performed; regardless of scan result suggestive of either presence or absence of lymphoma; patients were followed and histopathological findings of each patient was collected and recorded on Performa. Other demographic variables were also obtained and data were analyzed by Statistical Package for the Social Sciences [SPSS] -17
Results: Sensitivity, specificity, positive and negative predictive value as well as accuracy of computed tomography in the detection of neck andmediastinal lymphoma were found to be 75%, 89.9%, 59.2, 94.8% and 87.4% respectively. For patients with 10 months duration of disease, the accuracy of CT scan was observed as 84.7% and 93.6% respectively
Conclusion: CT scan is cross-section modality of choice for evaluating patients with suspected malignant tumors. CT is readily available and has high accuracy in distinguishing a mass compared with other tumors
ABSTRACT
Objective: To evaluate the role of CT scan of nasal cavity and paranasal sinuses in preoperative assessment of anatomical variants and in determining their frequencies
Materials and Methods: This descriptive study was done as a part of residency training for FCPS in the subject of Radiology on 132 patients who visited the hospital, Sindh Institute of Urology and Transplantation [SIUT] from March 2012 to April 2013. All CT scans were reviewed for presence of concha bullosa, variations of uncinate process, haller cell, onodi cells, aggernasi cells, ethmoid bulla, paradoxical middle turbinate, deviated nasal septum [DNS], pneumatization in the nasal septum, superior and middle turbinate, and uncinate process. Frequencies of all anatomical variants were calculated using SPSS version 16
Results: Deviated nasal septum was found to be the most frequent variant 31% followed by Concha bullosa 18.9% and variations in uncinate process 12%. Rhino sinusitis was found in all cases with paradoxical medial turbinate and patients with variation in uncinate process
Conclusion: CT scan can play an important role in preoperative assessment of variants and in determining their frequencies in nasal cavity and paranasal sinuses. It could be of great help for surgical planning and minimizing the surgical complications in patients