ABSTRACT
Heterocycles bearing a symmetrical triazole represent an interesting class of compounds possessing a wide spectrum of biological activities such as antiinflammatory, anticancer, antitubercular, antiviral and antimicrobial properties. In present study an attempt was made to synthesize compounds using propyl gallate and hydrazine hydrate as starting material. And following the scheme five different compounds using different aromatic substituents. Synthesized compounds were subjected to physical characterization and spectral analysis for structural confirmation. The compounds were than subjected to evaluation of antibacterial and antifungal activity. The bacterial screening indicated that among the test compounds number S2, S3, moderately activity against all the tested bacterial strains Bacillus subtilus, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae. The remaining compounds were found to be less active. Minimum inhibitory concentration value of the compounds against the bacteria stains reveals that compound S3, S4 have better onset of action against all bacteria strains as compared to that of standard. Antifungal screening revealed that the test compounds showed moderate activity against Aspergillus niger.