ABSTRACT
Bias is an inevitable part of study designs. Despite best efforts of research, scholars and authors biases are bound to occur in research methodology. The aim of this review article is to acquaint the dental authors with various types of bias and methods to reduce these in dental research. To understand the basics of different biases in dental research is hence essential to keep it to minimum in any research for the effectiveness of the study.
ABSTRACT
Research methodology has always been a matter of interest for epidemiologist, clinicians, biostatisticians and students for decades. Research vary in different spectrum of ways, methods and patterns for execution. Knowing the steps in study design, formulating research question and measuring the outcome forms the basis of this methodology of research. Sampling methods, types of data, measurement, sample collection, various test of significance often leads to arrival of many questions into the students and researchers mind. This article aims to provide a simple yet conclusive view on the different parameters and entities involved in performing research pertaining to prosthodontics.
ABSTRACT
Background: Denture-related stomatitis is probably the most common form of oral candidiasis and its reported prevalence varies widely ranging up to 65%. In this thorough study, we evaluate the effect of Delmopinol application on Candida albicans adherence on heat cured denture base acrylic resin. Materials and Methods: A total of 40 specimens of heat-cured acrylic resin were made, 20 specimens were contaminated before Delmopinol treatment and 20 specimens were contaminated after Delmopinol treatment. The each specimen in each tube was individually transferred to a spectrophotometer at 530 nm wavelength in order to measure the turbidity degree, through the transmittance. Aliquots of 10 μL of each tube was then collected and inoculated into agar sabouraud plates containing 500 mMol/L of sucrose, which was incubated for 24 hours at 37°C, in order to check microbial growth. Results: Mean of the turbidity Degree of contamination after Delmopinol application (1440.80, colony-forming unit [CFU] [×10 6 /ml]) was significantly higher than the mean of the turbidity degree of contamination before Delmopinol application (550.85 CFU [×10 6 /ml]). Conclusion: Heat-cured acrylic resin shows greater reduction in adherence of Candida albicans by contamination after Delmopinol application as compared with contamination before Delmopinol application.