ABSTRACT
Adenomyoepithelioma of the breast is a rare tumor. Malignant change arising in this lesion is infrequent and only a few cases have been reported. We discuss a case of a 56-year-old female presenting with a firm breast mass, which was interpreted as myoepithelial carcinoma arising in a background of adenomyoepithelioma, based on morphological and immunohistochemical studies. This case is being highlighted for its rarity and distinct morphological spectrum.
ABSTRACT
Acanthamoeba species are free-living amoebae that are the causative agents of chronic granulomatous meningoencephalitis, amoebic keratitis, pulmonary lesions, cutaneous lesions and sinusitis. Immunocompromised individuals are particularly susceptible to infections with Acanthamoeba, which can be disseminated at times. We herewith report the autopsy findings of disseminated Acanthamoeba infection in a 36-year-old female, a renal transplant recipient on immunosupressants for last four years. Central nervous system showed Acanthamoeba associated chronic granulomatous meningoencephalitis, with predominant perivascular infiltrate of amoebic cysts, trophozoites and inflammatory cells. Both lungs and pancreas also showed infiltration with Acanthamoeba.
Subject(s)
Acanthamoeba/pathogenicity , Adult , Amebiasis/diagnosis , Animals , Central Nervous System Protozoal Infections/diagnosis , Diagnosis, Differential , Female , Humans , Immunocompromised Host , Kidney Transplantation/adverse effectsABSTRACT
Nephrogenic adenoma is a rare benign tumour-like lesion within the urothelial mucosa of the urinary tract. It may be an incidental finding in bladder of a patient presenting with haematuria, dysuria and bladder growth after renal allograft transplant. Clinically it mimics bladder neoplasm. Definite diagnosis is established by histological examination of tumor. Though it attains an extensive spread in bladder mucosa and has a high tendency to recur, the clinical course is benign.