ABSTRACT
The principal cause of splenic vein thrombosis [SVT] is pancreatic disease. Isolated splenic vein thrombosis [ISVT] is a very rare complication of celiac disease. Only few cases are reported worldwide. Affected patients develop left-sided portal hypertension often complicated by splenomegaly and isolated gastric varices. The condition is usually asymptomatic, but patients may complain of non-specific abdominal pain. Gastric variceal bleeding in this context is uncommon but should it occur, it could be life threatening and splenectomy would be the treatment of choice. The role of anticoagulation is controversial and the risk of further thrombotic events must be balanced against that of variceal bleed. We report a case of a patient with celiac disease [CD] who presented with a new onset non-specific abdominalpain, who was found to have ISVT complicated by portal hypertension, splenomegaly and non-bleeding isolated gastric varices. He was successfully managed with anticoagulation
ABSTRACT
Hereditary spherocytosis is a familial hemolytic disorder of red cell membrane cytoskeleton characterized by anemia, jaundice and splenomegaly. There are very few cases on record, of spinal cord dysfunction associated with this disorder, which are considered to be due to an abnormality in the cytoskeletal protein present in red cells, neuronal and dendritic cell membranes. We describe a rare case of hereditary spherocytosis which presented with spinal cord dysfunction