ABSTRACT
Objective To determine the frequency of pruritic dermatoses among pregnant women.
Methods This, cross-sectional study was conducted at Obstetrics out-patient department, Bahawal- Victoria Hospital, Quaid-e-Azam Medical College, Bahawalpur, over a period of 6 months in 238 Pregnant women of age ranging from 20 to 40 years. Following specific pruritic dermatoses of pregnancy were searched and recorded on pre-designed proforma and analyzed: pemphigoid gestationis, polymorphic eruption of pregnancy, prurigo of pregnancy, intrahepatic cholestasis of pregnancy, eczema in pregnancy and pruritic folliculitis of pregnancy.
Results Among 238 pregnant women, 14 [5.9%] presented with pruritic dermatosis of pregnancy while in rest of 224 [94.1%] patients no specific dermatosis of pregnancy was found. Out of those 14 patients, polymorphic eruption of pregnancy was seen in 5 [35.7%] patients, eczema in pregnancy in 4 [28.6%], pemphigoid gestationis in 2 [14.3%], prurigo of pregnancy in 1 [7.1%], intrahepatic cholestasis of pregnancy in 1 [7.1%] and pruritic folliculitis of pregnancy in 1 [7.1%] patient. The dermatoses of pregnancy was detected in 5 [35.7%] patients in the age group 20-25 years, 4 [28.6%] patients of age group of 26-30 years, 2 [14.3%] patients of age group of 31-35 years and 3 [21.4%] patients of age group of 36-40 years of age.
Conclusion Pruritic dermatoses of pregnancy are not uncommon among pregnant women and should be considered while evaluating pregnant women. Polymorphic eruption of pregnancy is most frequent pruritic dermatosis of pregnancy, followed by eczema of pregnancy.
ABSTRACT
Objective To determine the frequency of cutaneous manifestations in patients suffering from hepatitis C infection.
Methods In this cross-sectional study, one hundred diagnosed patients of hepatitis C, admitted in medical units of Bahawal-Victoria Hospital, Bahawalpur, Quaid-e-Azam Medical College, Bahawalpur were registered over a period of six months. Cutaneous manifestations in these patients were recorded and analyzed.
Results Out of 100 patients, 51 [51%] were males and 49 [49%] were females. Majority of the patients [73%] were 20 to 59 years old. Most of the patients had more than one cutaneous manifestation. These included generalized pruritus 30%, lichen planus 30%, urticaria 26%, leukocytoclastic vasculitis 25%, necrolytic acral erythema 20% and porphyria cutanea tarda 4%.
Conclusion Cutaneous manifestations of hepatitis are not uncommon. These may be the first clinical sign of chronic hepatitis C infection. Generalized pruritus, lichen planus, urticaria, leukocytoclastic vasculitis, necrolytic acral erythema and porphyria cutanea tarda were the important cutaneous manifestations recorded. Screening such patients on the basis of these dermatoses and investigating accordingly may help in early diagnosis and prevention of complications of this grave disease.