1.
Article
in English
| IMSEAR
| ID: sea-177608
ABSTRACT
Objective: To review genetic cause of developmental disorders. Methodology: A survey consisting of 70 children with developmental disorder was done for genetic evaluation of these disorders through case history and interview of the parents. Results: The cause was found to be combination of genetic variation with environmental risks due to which epigenetic changes might have taken place in prenatal stages in 81% of the cases in the survey. Only 16% of cases showed mendelian inheritance. Conclusion: The results indicate that developmental disorders are of epigenetical nature rather than mendelian inheritance.