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Article in English | IMSEAR | ID: sea-41933

ABSTRACT

OBJECTIVES: To determine response, complication and survival of uterine cervical cancer patients treated with concurrent gemcitabine radiotherapy. MATERIAL AND METHOD: A retrospective review of medical records of 41 patients with uterine cervical cancer patients, stage IIB and above treated with concurrent gemcitabine radiotherapy from August 2000 to August 2003. RESULTS: At 6 and 12 months of follow up, the complete response rate was 75.6% and 65.9%. The cumulative probability of survival at 6 and 12 months after treatment was 0.93 and 0.85. The main complications were mild hematologic and nonhematologic toxicities. CONCLUSION: Concurrent gemcitabine radiotherapy provided a satisfactory response in patients with uterine cervical cancer with mild toxicity. Long term follow up data is necessary to determine the recurrent rate of this regimen.


Subject(s)
Adult , Aged , Antimetabolites, Antineoplastic/therapeutic use , Carcinoma/drug therapy , Combined Modality Therapy , Deoxycytidine/analogs & derivatives , Female , Humans , Middle Aged , Retrospective Studies , Survival Rate , Thailand , Treatment Outcome , Uterine Cervical Neoplasms/drug therapy
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