Reversible neonatal renal failure associated with maternal use of captopril

We report a case of neonatal hypotension and reversible renal failure in a newborn, delivered to a mother who was known to have hypertension. The mother required a battery of anti-hypertensives including captopril, through pregnancy until delivery. We agree with other reports that there is a possible association of acute neonatal renal failure following maternal use of captopril

Pattern of bacterial flora in neonates in Dubai

Of 310 neonates in SBCU in Rashid and Al Wasl Hospitals studied over an 8 months period, there were 252 positive cultures from different sites. E-coli was the most common organism isolated in 54 patients [21.42%] followed by Staph aureus in 46 [18.25%]. Then in decreasing order of frequency were Pseudomonas in 44 patients [17.46%]; Staph albus 31 [12.30%], Klebsiella 29 [11.50%] and Strept Group B in 26[10.31%]. Serratia, enterobacter, Strept faecalis, Flavobacterium, Shigella, Haemophilus, Acinetobacter and Citrobacter were rarely isolated. Positive cultures were also studied for sensitivity against commonly used antibiotics. Pseudomonas was highly sensitive against carbenicillin, tobramycin and amikacin. E-coli was sensitive to ceftriaxone and amikacin 100%; tobramycin 95.8% but resistant strains against Ampicillin were 88.4%. Staph aureus was highly sensitive to cloxacillin and all usual aminoglycosides. Staph albus was also 100% sensitive to cloxacillin and all usual aminoglycosides. Klebsiella had good sensitivity against ceftriaxone and netilmicin but was totally resistant to Ampicillin