ABSTRACT
The purpose of this study was to determine the gender differences in the Presentation of Acute Myocardial Infarction. Observational study. National Institute of Cardiovascular Diseases - Karachi, study was carried outfrom 1st Sept. 2006 to 31st December 2006. Consecutive 1008 patients were included in this study with definite evidence of first episode of AMI. There were 758 [75.1%] men and 250 [24.8%] women. Women were on average 7 years older than the men [58 vs 51 years, p=<0.01]. 13% of female patients were menstruating while 87% were non-menstruating. 9.3% of our patients were under the age of 40 years. 13% of women and 9% of men were obese. Women more frequently had hypertension [67% vs 37%, p=<0.001], DM [38% vs 22%, p=<0.001]. More of the men were cigarette smokers [60% vs 8%, p = <0.001]. Women had more in-hospital complications [38% vs 25%, p= <0.01], and mortality [13.4% vs 5.5%, p = <0.001]. Women were less likely than men to be eligible for thrombolytic therapy [54% vs 77%]. These results indicates that women were 6 years older than men presented with AMI and more likely to have hypertension, DM and Pre-infarction angina. The in-hospital complication and mortality were higher in female patients than male. Less women were elegible for thrombolytic therapy on arrival compared to men