Subject(s)
Humans , Male , Adult , Prostate , Prostatic Neoplasms , Adenocarcinoma , Radiotherapy , Drug TherapySubject(s)
Humans , Female , Middle Aged , Pelvic Exenteration , Urethra , Urethral Neoplasms , AdenocarcinomaSubject(s)
Humans , Female , Middle Aged , Urethra , Urethral Neoplasms , Adenocarcinoma , Cell Transformation, Neoplastic , Diverticulum , Carcinoma , Neoplasm MetastasisABSTRACT
ABSTRACT Objectives: This study aims to verify the new-onset diabetes after kidney transplant (NODAT) incidence in recipients within 1 year after kidney transplantation from a single center in Southern Brazil and to assess the associated conditions. Subjects and methods: A retrospective study of 258 post-renal transplant patients was performed. Demographic (gender, age, ethnic background) and clinical (origin of graft, associated infections, body mass index (BMI) at transplant time and 6 and 12 months after, causes of renal failure, and comorbidities) data were analyzed. All patients were on tacrolimus, mycophenolate mofetil, and prednisone treatment. Patients with and without NODAT were compared. Results: A NODAT incidence of 31.2% was noted 1 year post transplantation. In the univariate analysis, patients with NODAT were older (p = 0.001), mostly had African-American ethnic background (p = 0.02), and had renal failure secondary to high blood pressure (HBP) (p = 0.001). The group of patients with NODAT also had more incidence of post-transplant HBP (p = 0.01), heart failure (p = 0.02), and dyslipidemia (p = 0.001). Logistic regression showed that African-American ethnic background, post-transplant HBP, and dyslipidemia were independently associated with NODAT. Conclusion: This study shows a NODAT incidence that is greater in patients with African-American ethnic background and that is associated with HBP and dyslipidemia.
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Postoperative Complications/etiology , Kidney Transplantation/adverse effects , Diabetes Mellitus/etiology , Postoperative Complications/epidemiology , Brazil/epidemiology , Logistic Models , Incidence , Retrospective Studies , Risk Factors , Tacrolimus/adverse effects , Statistics, Nonparametric , Diabetes Mellitus/epidemiology , Dyslipidemias/etiology , Hypertension/etiology , Immunosuppressive Agents/adverse effectsABSTRACT
ABSTRACT Objective The objective of this study was to correlate the values of abdominal circumference (AC) and body mass index (BMI) with the levels of total testosterone (TT), free testosterone (FT) and sexual hormone binding globulin (SHBG). We aimed to analyze the association between the anthropometric values and variations in the hormonal levels. Subjects and methods A transversal prospective study was conducted. A total of 159 patients were included in the study. Results BMI was inversely correlated with TT and SHBG (p = 0.02 and p = 0.006, respectively). AC was also inversely correlated withTT and SHBG (p = 0.006 and p < 0.0001, respectively). However, BMI did not correlate signicantly with these hormonal levels after adjusting for age. Conclusion This finding led to the conclusion that AC had a stronger inverse correlation than BMI with TT and SHBG. Our data suggested that AC alone can be used as an anthropometric parameter to help simplify the identification of men with low serum TT levels.