ABSTRACT
Results of the experiment conducted in sandy loam soils during 2006-07 and 2007-08 revealed that quality parameters of cane juice and jaggery were positively and significantly influenced by the application of sulphur irrespective of sources of sulphur. Application of sulphur at 100kg/ha had significantly influenced the quality of juice but it was comparable with the application of sulphur at 80kg/ha which was reflected in quality of jaggery. There is an increase of 1.27 units in juice sucrose was observed with the application of sulphur at 80kg/ha. But sources did not differ markedly on juice quality and jaggery quality parameters. As Gypsum is cheapest source compared to Elemental sulphur, it can be concluded that maximum returns can be obtained at 80 kg S/ha through Gypsum application.
ABSTRACT
Three simple, sensitive and accurate methods are described for the determination of 7-Amino deacetoxy cephalosporanic acid (7-ADCA) in bulk drug and in formulations. Methods Ma to Mc are based on Redox / complex formation reaction between 7-ADCA and ammonium Molybdate and sulphuric acid (AM/H2SO4) (Ma), Ferric chloride/ Ortho Phenonthraline (Fe+3/o-Phen)(Mb) and FeCl3/potassium Ferricyanide (Fe+3/K3Fe(CN)6) (Mc) solutions. The chromogen being extractable with chloroform could be measured quantitatively at 625 (Ma), 510 (Mb) and 740 nm (Mc). All variables were studied to optimize the reaction conditions. Regression analysis of Beer's Law plot showed good correlation in the concentration ranges 10-60 for Ma, 1.25-7.5 for Mb and 2.5-15 mg/ml for Mc. The calculated molar absorptivity values are 2.835 x 103, 2.277 x 104, and 1.715 x 104 L/mol/cm for Ma to Mc, respectively. The methods were successfully applied to the determination of 7- ADCA in formulations and the results tallied well with the label claim. The results were statistically compared with those of a literature method by applying the student’s t-test and F-test. No interference was observed from the concomitant substances normally added to preparations. The accuracy and validity of the methods were further ascertained by performing recovery experiments via standard-addition method.