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1.
Medisan ; 19(6)jun.-jun. 2015.
Article in Spanish | LILACS, CUMED | ID: lil-752951

ABSTRACT

Aproximadamente hasta 30 % de todos los pacientes con cáncer de colon, intervenidos con intención curativa, presentarán enfermedad recurrente, la cual puede provocar la muerte o motivar nuevos tratamientos con alto grado de morbilidad, sin que se haya logrado definir un modelo efectivo sobre la conducta a seguir, habida cuenta que aún no existen criterios uniformes con respecto a su prevención, tratamiento y seguimiento posoperatorio luego de la cirugía inicial, por cuanto se desconocen las posibilidades reales de supervivencia y las causas asociadas a la mortalidad. Sobre la base de tales reflexiones, se revisó la bibliografía pertinente sobre algunas cuestiones elementales al respect.


Approximately up to a 30% of patients with colon cancer, surgically treated with healing aims, will have a recurrent disease, which can cause death or motivate new treatments with high morbidity degree, without achieving yet a definite and effective model on the behaviour to be followed, taking into account that there are no uniform approaches with regard to its prevention, treatment and postoperative follow-up after the initial surgery, so that the real possibilities of survival and the causes associated with mortality are ignored. On the basis of such conclusions, the pertinent literature was reviewed on some elementary questions in this respect.


Subject(s)
Colonic Neoplasms , Colonic Neoplasms/diagnosis , Radiotherapy , Colonic Neoplasms/mortality , Drug Therapy , Immunotherapy
2.
Medisan ; 19(2)feb.-feb. 2015. tab
Article in Spanish | LILACS, CUMED | ID: lil-735263

ABSTRACT

Se realizó un estudio descriptivo y observacional de 37 pacientes operados de cáncer de colon, con intención curativa, y que presentaron recurrencia tumoral, atendidos en el Hospital Clinicoquirúrgico Docente "Saturnino Lora Torres", de Santiago de Cuba, durante el período 2006-2012, con vistas a identificar algunos aspectos relevantes relacionados con el diagnóstico del cáncer de colon recurrente. Predominaron las mujeres mayores de 65 años, el tumor primario en el colon ascendente, con estadificación posoperatoria III y II, la recurrencia locorregional, así como el tumor palpable como forma de presentación. El método clínico, la ecografía y la radiografía por enema fueron determinantes para el diagnóstico. Se concluye que durante los primeros 2 años del seguimiento posoperatorio deben agotarse todos los medios para el diagnóstico precoz de dicha recurrencia, independientemente de su localización.


A descriptive and observational study of 37 operated patients due to colon cancer, with healing purposes, and who presented tumorous recurrences, assisted in "Saturnino Lora Torres" Teaching Clinical Surgical Hospital, in Santiago de Cuba was carried out during the period 2006-2012, with the objective of identifying some outstanding aspects related to the diagnosis of recurrent colon cancer. Women older than 65 years, the primary tumour in the ascending colon, with postoperative staging III and II, the locorregional recurrence, as well as the palpable tumour as presentation form prevailed. The clinical method, the echography and the x-ray for enema were decisive for the diagnosis. It is concluded that during the first 2 years of the postoperative follow-up all means should be used for the early diagnosis of this recurrence, independently from its localization.


Subject(s)
Recurrence , Colonic Neoplasms , Colonic Neoplasms/surgery , Colonic Neoplasms/diagnosis , Drug Therapy
3.
Medisan ; 18(11)nov.-nov. 2014. ilus, tab
Article in Spanish | LILACS, CUMED | ID: lil-728421

ABSTRACT

Se realizó un estudio descriptivo de 37 pacientes operados de cáncer de colon con intención curativa y que presentaron recurrencia tumoral, atendidos en el Hospital Provincial Docente Clinicoquirúrgico "Saturnino Lora Torres", de Santiago de Cuba, durante el período 2006-2012, con vistas a identificar los factores asociados al intervalo libre de enfermedad luego de la cirugía inicial. En la casuística predominaron los afectados mayores de 65 años, del sexo femenino; el tumor primario localizado en el colon derecho con estadificación posoperatoria III y II, la recurrencia locorregional como la de mayor frecuencia y el tumor palpable como el más común. El método clínico, la ecografía y la radiografía de colon por enema fueron determinantes para el diagnóstico. El tratamiento exerético del cáncer de colon asociado a la quimioterapia adyuvante garantizó un intervalo libre de enfermedad más prolongado, si bien el diagnóstico de la recurrencia se correspondió con la detección temprana durante el período posoperatorio, la cirugía fue esencialmente paliativa.


A descriptive study of 37 operated patients of colon cancer with healing intention and who presented tumoral recurrence, assisted in "Saturnino Lora Torres" Teaching Clinical Surgical Provincial Hospital, in Santiago de Cuba was carried out during the period 2006-2012, aimed at identifying the factors associated with the interval free of disease after the initial surgery. The affected patients older than 65 years, female sex; a primary tumour located in the right colon with postoperative stage III and II, local-regional recurrence as that of greater frequency and a palpable tumour as the most common, prevailed in the case material. The clinical method, echography and colon x-ray for enema were decisive for the diagnosis. The exeresis of the colon cancer associated with the adjuvant chemotherapy guaranteed a longer interval free of disease, although the diagnosis of recurrence was in correspondence with the early detection during the postoperative period, the surgery was essentially palliative.


Subject(s)
Recurrence , Colonic Neoplasms , Postoperative Period , Secondary Care , Radiography , Chemotherapy, Adjuvant
4.
Medisan ; 18(10)oct.-oct. 2014. ilus
Article in Spanish | LILACS, CUMED | ID: lil-727578

ABSTRACT

Se efectuó un estudio observacional, descriptivo y longitudinal de 37 pacientes operados de cáncer de colon, con intención curativa, en el Hospital Clinicoquirúrgico Docente "Saturnino Lora Torres" de Santiago de Cuba, durante el período 2006-2012, quienes presentaron recurrencia tumoral diagnosticada en consulta externa mediante un esquema de seguimiento posoperatorio durante un quinquenio o más, con vistas a identificar algunos factores asociados a la supervivencia. Entre los principales resultados de la serie, se obtuvo que la recurrencia tumoral loco-regional fuese predominante y la nueva intervención quirúrgica junto a la quimioterapia adyuvante devino mayor supervivencia en comparación con la alcanzada al emplear solo agentes químicos. Por otro lado, la mayoría de los afectados alcanzaron una supervivencia no mayor de un año, tomando en cuenta el intervalo desde el diagnóstico hasta el deceso, y al finalizar el estudio existía una mortalidad de 62,2 %, cuya causa más frecuente fue la propia recurrencia tumoral. Pudo concluirse que las intervenciones fueron en esencia paliativas, si bien el diagnóstico se correspondió con la detección temprana durante el período de seguimiento posoperatorio.


An observational, descriptive and longitudinal study of 37 patients operated from colon cancer was made, with healing intention, in "Saturnino Lora Torres" Teaching Clinical Surgical Hospital in Santiago de Cuba, during the period 2006-2012 who presented tumorous recurrence diagnosed in the out-patient department, by means of an outline of postoperative follow up during a five year period or more, with the aim of identifying some factors associated to the survival. Among the main results of the series, it was obtained that the local-regional tumorous recurrence was predominant and the new surgery together with the adjuvant chemotherapy caused a greater survival in comparison to the one reached when using just chemical agents. On the other hand, most of the affected patients reached a survival no longer than one year, taking into account the interval from the diagnosis to death, and when concluding the study there was a mortality of 62.2%, whose most frequent cause was the tumorous recurrence itself. It could be concluded that surgeries were essentially palliative, although the diagnosis was in correspondence to the early detection during the period of postoperative follow up.


Subject(s)
Recurrence , Colonic Neoplasms , Aftercare , Surgical Procedures, Operative , Survival , Survivorship
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