The Clinical Effectiveness of Cervicography in Cervical Cancer Screening / 대한부인종양콜포스코피학회잡지

In an effort to reduce the false-negative rate of PAP smear, several new technologic screening methods have recently evolved. Cervicography is one of these methods. The purpose of this study was to evaluate the screening use of cervicography as an adjunctive method and the clinical effectiveness of cervicography in korean reports, compared with other countries. And we estimated the specificity and sensitivity of cervicography in cervical cancer screening in several korean reports. The results were : 1. The sensitivity of cervicography and pap smear was 89.2% and 85.7%. 2. The false negative rate of cervicography and pap smear was 3.8% and 22.4%. 3. When cervicography and Pap smear were used conjointly, the sensitivity was higher than for cervicography or pap smear used alone(95.7% vs 89.2%, 95.7% vs 85.7%) Cervicography is one of the useful screening method for detect cervical cancer, However when cervicography are used in conjunction with Pap smear, the detection rate of cervical cancer will be increased.

Acute Interstitial Pneumonia (Hamman-Rich Syndrome): An Autopsy Case

Acute interstitial pneumonia is a fulminant disease of unknown etiology that usually occurs in a previously healthy person and produces the histologic findings of the organizing phase of diffuse alveolar damage. We experienced an autopsy case of acute interstitial pneumonia of unknown etiology. The patient was a 48 year old man who had been healthy and had not been exposed to organic dusts or other toxic materials. The chief complaints represented were dyspnea and a dry cough for several weeks before hospitalization, and the chest radiographs showed bilateral interstitial infiltrates. Patchy consolidation of air space was also identified and ground-glass attenuation similar to those described in ARDS was detected on high-resolution computed tomography. Steroid pulse therapy, mechanical ventilation, and antibiotics for superimposed bacterial infection were performed, but the symptoms did not improve and the patient died of generalized respiratory insufficiency and severe hypoxemia 2 1/2 months after hospitalization. At autopsy the macroscopic and microscopic findings were confined mainly to the lungs. On the whole, both lungs were firm in consistency and the external surface showed a cobblestone appearance. The cut surface showed almost complete replacement of the normal lung parenchyma with gray to yellow fibrous tissue with a little residual functional area remaining. The pathology of both open lung biopsy and autopsy tissue showed marked hyperplasia of type II pneumocytes, hyaline membrane formation, thickening of the alveolar wall due to extensive fibroblast proliferation, and relatively abundant young collagen deposition in the interstitium. An immunohistochemical stain for cytokeratin revealed epithelial hyperplasia and showed that the alveolar spaces were markedly shrunken by fibrous tissue.