Prevalence of biofilm producing MDR candida albicans and non candida albicans isolate from medical devices.

Totally 56% of occurrence was observed from 6 types of sources. Among them highest prevalence was observed from urinary catheter (68%) next in line is intravenous tubes (66.66%), venflon needles (65%), and blood bags (53.33%) respectively. Four types of Candida species were identified by using selective media and biochemical tests. The Candida albicans was predominant isolates in all sources especially in urinary catheter. In this study, 60.2% of non Candida albicans were observed. All isolates were subjected to antifungal stability test, 6 antifungal agents were used. Among the 6 antifungal agents Itraconazole had highly resistance activity and Fluconazole had highly sensitive activity against the isolates. The antifungal resistance of isolates were highly observed in non Candida albicans such as Candida tropicalis (83.3%) and followed by Candida glabrata (74.5%). All isolates were have the ability to produce biofilm, among them 37.4% of isolates were strong biofilm producer and 100% of protease producing isolates were observed in the last part of the study.

Emergence of multi drug resistant strains of E. Coli isolated from urinary tract infection in namakkal.

In this study we evaluated the multi drug resistant strains of Escherichia coli isolated from urinary tract infection in different age groups in Namakkal. Totally 153 isolates of E.coli were obtained from 700 urine samples. Present study indicates that there is a high prevalence of multidrug resistant E. coli in female 24.34% followed by male 18.14%. After confirmation, isolates were performed to resistance patterns of different antibiotics were determined by standard disk diffusion method. The antibiogram patterns of the isolates showed a high percentage of multidrug resistance to cephodoxime, Novobiocin and vancomycin which was repeated to most of the isolates. Fifty resistance patterns were recognized among the MDR strains. This study revealed that E. coli was the predominant bacterial pathogen of community acquired UTIs in Aligarh, India. It also demonstrated an increasing resistance to number of antibiotics. This study is useful for clinician in order to improve the empirical treatment.