A Case of Congenital Epulis of the Newborn

Congenital epulis of the newborn refers to a very rare gingival tumor that occurs along the anterior alveolar ridge in newborn infants. We report a neonate with 3*2*1.5cm mass protruding from the mouth. This was a pinky, red solid pedunculated mass, attached to the maxillar left canine region of the alveolus at birth. The tumor's large size partially obliterated the oral cavity and caused oral feeding difficulty but did not cause respiratory problems. We described the postnatal MR imaging findings, electromicroscopic, histochemical and immunohistochemical studies of this tumor in order to search for the histogenesis of the tumor. In our case, histochemically, individual tumor cells contained numerous PAS positive cytoplasmic granules. Immunohistochemically, strong and diffuse cytoplasmic staining for vimentin and NSE was observed. Staining with S-100 protein, cytokeratin, desmin, CEA, factor VIII-related antigen, lysozyme, EMA were negative. After total excision of the lesion in our case, we had no complication or recurrence either early or late(up to one year).

A Case of Catel Manzke Syndrome

Catel Manzke syndrome is characterized by hyperphalangy of the index fingers associated with Robin malformation sequence. The etiology of Catel Manzke syndrome is still uncertain, with the majority of cases being sporadic. Careful observation to recognize upper airway obstruction secondary to the Robin sequence should be made a part of routine care for newborns with this disorder. Failure to thrive is related to respiratory or cardiac problems. The vast majority of case have normal intelligence. With advancing age, the accessory bone fuses to the proximal phalangeal epiphysis. We report a neonate with the Pierre Robin triad, accessory bone between the second metacarpal and its proximal phalanx of the Rt hand, camptodactyly, coarctation of aorta and hydronephrosis of Lt kidney.