ABSTRACT
<p><b>OBJECTIVE</b>To probe into the feasibility and accuracy of sentinel lymph node biopsy by subareolar injection of blue dye in the treatment of early-stage breast carcinoma.</p><p><b>METHODS</b>Retrospective analysis of 25 cases of early-stage breast cancer who were carried out subareolar injection of blue dye method for sentinel lymph node biopsy.</p><p><b>RESULTS</b>Of 25 cases, 24 were checked out sentinel lymph nodes. Check-out rate was 96.0%. Totally 62 sentinel lymph nodes were checked out, each patient had 2.5 nodes averagely. There were 5 cases with lymph node metastases in HE stain, and 7 cases with positive nodes in IHC stain. Sensitivity in this group was 87.5%; Accuracy 96.0%; False negative rate 12.5%; False positive rate 0.</p><p><b>CONCLUSION</b>Application of sentinel lymph node biopsy by subareolar injection of blue dye in the treatment of early-stage breast carcinoma can also acquire high check-out rate and high accuracy.</p>