ABSTRACT
Background and purpose: Adenocarcinoma is the main type of lung cancer and the ages of most patients with adenocarcinoma are over-40 years, the young patients with the disease are rare, and the 5-year survival rate of the young male with lung adenocarcinorna is poor. This study was done to explore the survival and prognosis of young male with lung adenocarcinoma. Methods: A total of 110 surgically treated patients with lung adenocarcinoma were analyzed retrospectively to study the relationship between the prognostic factors and survival. Results: The analysis showed that the overall 5-year survival rate of the young male with lung adenocarcinoma was 34.5%, it was 29.0% for smokers and 42.6% for non-smokers(P<0.05). The 5-year survival rates of staging Ⅰ, lI ,Ⅲ and Ⅳ were 68.8%,35.7%, 14.3% and 0, respectively(P<0.01),the survival rates of the patients with the number of involved lymph nodes>3 compared to ≤3 were 28.5% and 48.1%(P<0.01). Conclusion: Smoking, p-TNM, the number of involved lymph nodes was correlated with the survival, effective smoking control efforts and total lymphadenectomy are important to the survival of lung adenocarcinoma among young males.