ABSTRACT
<p><b>OBJECTIVE</b>To study the effects of noise on bioactivity of norepinephrine (NE) and cardiovascular system.</p><p><b>METHODS</b>A total of 130 workers exposed to the occupational noise in one enterprise were selected as noise exposure group, and 134 workers not exposed to the occupational noise and other poisons served as control group. Fasting venous blood was drawn to determine the content of NE in peripheral blood with ELISA. According to Occupational Health Surveillance Manage regulations, the occupational noise exposures crowd was examined.</p><p><b>RESULTS</b>The average of NE in exposure group was (0.1387 +/- 0.099) ng/ml, and (0.1019 +/- 0.080) ng/ml in control group. There was significant difference in NE between exposure and control group. There was significant difference in the detection rate of BP, HR and ECG between exposure and control group.</p><p><b>CONCLUSION</b>The occupation noise can increase the NE in peripheral blood, and maybe affects the cardiovascular system in this way.</p>