ABSTRACT
AIM:To investigate the curative effect of 1 g/L bromfenac sodium eye drops on high myopia astigmatism in patients after sub-Bowman keratomileusis.· METHODS:Totally 48 cases (96 eys) of High myopic astigmatism (-6.00D＜ equivalent sphere＜-11.00D) from our hospital were selected and randomly divided into 2 groups,24 cases(48 eyes) each.The control group was treated with fluorometholone eye drops,the experimental group was treated with 1g/L bromfenac sodium eye drops,and 2 groups were treated for 2wk.Uncorrected visual acuity,intraocular pressure and corneal topography (K1,K2,the degree of astigmatism) were recorded,at the same time visual symptoms and signs score,corneal haze and DLK were compared at preoperative and postoperative 1d,1wk,1 and 3mo.RESULTS:At different time points,uncorrected visual acuity,intraocular pressure,K1 value,K2 value,the degree of astigmatism of the two groups were statistically significant (P ＜ 0.05).Compared with preoperative,distance visual acuity increased at postoperative 1d,1wk,1 and 3mo;at postoperative 1 and 3mo intraocular pressure decreased(P＜0.05).Compared with the control group,the patients in the experimental group had better uncorrected visual acuity at postoperative 3mo and lower intraocular pressure at postoperative 1 and 3mo(P＜0.05).Compared with preoperative,K1,K2 value of two groups decreased at postoperative 1 and 3mo,the degree of astigmatism increased(P＜0.05).There was no significant difference in K1,K2 and astigmatism between the two groups at postoperative 1 and 3mo (P＞ 0.05).The symptoms and signs of the two groups were similar,and there was no haze phenomenon after operation.The DLK evaluation of the experimental group was better than that of the control group (P＜0.05).CONCLUSION:The 1 g/L bromfenac sodium eye drops and fluorometholone eye drops have similar efficacy in the treatment of SBK after operation,but it can effectively reduce the risk of DLK and intraocular pressure,avoid the adverse reactions caused by glucocorticoid,and is an effective treatment plan.