ABSTRACT
Objective:To extract the effective components from medical materials using modern preparation technology and to stud-y the preparation process to obtain Qingwen Tuire granules, and establish the quality standard. Methods:The medical materials in the formula were extracted by a heating decoction method. The wet granulation process was used for the granule preparation. The compo-nents including bupleurum, paeoniae alba, scutellaria baicalensis and indigowoad leaf in the granules were identified by TLC and the contents of seutellarin in the preparation was determined by HPLC. Results:The characteristic spots in TLC were clear without any in-terference. The linear range of scutellarin was 0. 194-1. 164 μg with the correlation coefficient of 0. 999 5. The average recovery was 100. 89%(RSD=0. 74%, n=6). Conclusion:The methods used in the identification and quantification are sensitive, simple and ac-curate, which can be used in the quality control of Qingwen Tuire granules.