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Chinese Journal of Biochemical Pharmaceutics ; (6): 299-301, 2017.
Article in Chinese | WPRIM | ID: wpr-612722

ABSTRACT

Objective To explore the effects of nifedipine combined with Magnesium Sulfate on the serum of patients with hypertension of pregnancy blood creatinine, uric acid and serum cystatin C level.Methods68 cases of patients with pregnancy induced hypertension from December 2013 to December 2015 in our hospital were selected, according to the different treatment methods were divided into control group and experimental group, 34 cases in each group, the two groups were treated with conventional therapy and symptomatic treatment, the control group was given 25% Magnesium Sulfate Injection 20mL+5%, Glucose Injection 20mL, 8~10min intravenous injection, after 25% Magnesium Sulfate Injection 60mL+5% Glucose Injection 500mL intravenous drip, 1~2g/L,1 times a day, Phentolamine Mesilate Injection 20mg+5%, Glucose Injection 250mL intravenous drip, 30min drop, 1 times a day;The experimental group was given the Extended Release Nifedipine Tablets 30mg sublingual in the control group on the basis of 3 times a day.Two group of gestational age<38 weeks treatment time was seven days,, the end of pregnancy over 38 weeks of treatment time was three days.After treatment the clinical efficacy, serum creatinine, uric acid, cystatin C, alpha-fetoprotein and adverse pregnancy outcome were compared between the two groups.ResultsAfter treatment,compared with the control group, the total effective rate of treatment group was higher (P<0.05), 2 groups of the blood serum uric acid, creatinine, Cystatin C and AFP levels were decreased (P<0.05), compared with the control group, the experimental group of serum uric acid, serum creatinine, Cystatin C and alpha fetoprotein level was lower (P<0.05).The experimental group, the complication rate was 5.88%, incidence rate of complications in the control group 14.71%, 2 groups of adverse pregnancy outcome rate comparison, the difference was not statistically significant.ConclusionNifedipine combined with Magnesium Sulfate significantly on clinical efficacy in patients with pregnancy induced hypertension, decrease the level of serum creatinine, uric acid and serum cystatin C levels, improve the quality of pregnancy, drug safety is high.

2.
Chinese Medical Equipment Journal ; (6)1989.
Article in Chinese | WPRIM | ID: wpr-591321

ABSTRACT

Objective To discuss the influence of Open resetlogs on Oracle database recovery. Methods Database backup was used to recover database before resetlogs. Before Oracle 9i, Oracle database was recovered through two steps; after Oracle10g, Oracle archived redo log by new format. Results Both methods could recover Oracle database by using backups before resetlogs. Conclusion Before Oracle9i, the recovery steps are complex, so it is suggested a consistent database backup should be made after resetlogs. By using the new archived redo log format after Oracle10g, it is easy to recover database through resetlogs.

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