ABSTRACT
The application of DNA technologies has rendered DNA analysis an important tool since the DNA fingerprint technology has been reported. Nowadays, with the rapid development of next generation sequencing (NGS) technology, the ability of forensic DNA analysis has been greatly extended by incorporating bioinformatics technique with forensic application. This paper reviews the research status and application prospects of bioinformatics in genomics, epigenetics and transcriptomics related to forensic genetics.
ABSTRACT
MicroRNA has speciifc biological and expression properties in transcription level, which has more potential than genomic DNA in the identification for forensic body fluid, species and degraded crime biological materials. Here we introduce the speciifc research of forensic body lfuid identiifcation, research strategies and applied perspectives with forensic miRNA, expecting to provide the application and study of miRNA analysis for reference.
ABSTRACT
Objective To apply the real-time quantitative PCR assay with the TaqMan Probe to DNA analysis in Forensic science . Methods Using the TaqMan method to quantitate DNA abstracted from variety of biological samples common in Forensic science . Results The quantity of sample DNA can be obtained. Inhibiting factors in the abstracted DNA might be evaluated. And subsequent procedures of STR testing were then directed. Conclusion Real-time quantitative PCR is a necessary technique for DNA analysis in Forensic science.