ABSTRACT
Objective:To investigate the effect of modified cervicothoracic compression band on successful hemostasis and postoperative complications of patients with endoscopic radical thyroidectomy via breast areola approach and to provide reference for postoperative nursing of thyroid cancer.Methods:A total of 128 patients with endoscopic radical thyroidectomy via breast areola approach from October 2018 to October 2019 in the Second Affiliated Hospital of Zhejiang University School of Medicine were selected and divided into experimental group(64 cases) and control group (64 cases) by random digits table method. Patients in the control group were fixed with wide adhesive tape for hemostasis, while patients in the experimental group wore modified cervicothoracic compression band. The postoperative complications between two groups were recorded, in addition, the physical condition and comfort of patients was assessed by Edmonton Symptom Assessment System (ESAS) and Kolcaba General Comfort Questionnaire (GCQ), respectively.Results:There was no sigrificance in the score of ESAS, GCQ on the 1st day before the operation between the two groups ( P>0.05). The median score of happiness in ESAS was 6.0 points in the experimental group on the 3rd day after the operation, significantly higher than 4.0 points in the control gorup, the difference was statistically significant ( Z value was 2.919, P<0.01). The physiological, psychological, social, cultural and environmental comfort, total GCQ scores were (10.73±2.35), (24.41±4.99), (23.09±2.11), (20.17±2.32), (78.41±6.49) points in the experimental group and (8.41±2.23), (22.42±4.79), (21.22±2.73), (19.20±2.97), (71.25±6.92) points in the control group, the differences were statistically significant ( t values were 2.058-6.031, P<0.05 or 0.01). The incidence of contact dermatitis, pressure purpura and tension blister were 0, 3.1% (2/64), 0 in the experimental group and 6.3% (4/64), 12.5% (8/64), 7.8% (5/64) in the control group, the differences were statistically significant ( χ2 values were 4.129, 3.095, 5.203, P<0.05). Conclusions:Modified cervicothoracic compression band can significantly alleviate the symptoms of postoperative patients with endoscopic radical thyroidectomy, reduce postoperative complications and improve patient comfort.
ABSTRACT
ObjectiveTo investigate the establishment of a rat model of orthotopic liver transplantation with more complete and easier performance of graft perfusion and easier control of warm ischemic time. MethodsA modification of Kamada two-cuff method was used. Cold perfusion of donor livers was done through the (ascending) aorta. Suture anastomosis of suprahepatic vena cava was performed. Infrahepatic vena cava and (portal) vein anastomoses were done by the cuff technique. The bile duct was anastomosed with internal stent. The non-heart-beating donor(NHBD) graft model of orthotopic liver transplantation in rats was thus (established).ResultsThe survival rate of recipients grafted from NHBD with perfusion of ascending aorta was 95% (38/40) for 1 day and 85.5% (35/40) for 7 days. ConclusionsThe livers of NHBD as grafts harvested with perfusion through ascending aorta had more complete and homogeneous perfusion, perfusion was easier to perform and warm ischemia time was more accurately controlled. The one-week posttransplantion (survival) rate was longer than that reported in the literature.
ABSTRACT
Objective To investigate the expression of hyperthermia-induced HSP70 in liver during the different period after heating. Methods SD rats were divided randomly into tow groups:Group A (room control group),rats′ liver tissues were removed at the 4 h,8 h,24 h,36 h and 72 h after anaesthesia respectively.Group B(hyperthermia group) rats were heated up by self-designed heating device (42℃,20 min),and then those liver tissues were harvested at the different time respectively as in the group A. Results HSP70 expression in livers of group B were significantly higher than that in group A(P