ABSTRACT
Objective To study correlation between oxygen uptaking efficiency and exercise endurance of patients with stable chronic obstructive pulmonary disease (COPD).Methods From January 2013 to December 2014,50 patients with COPD plateau were selected as the research subjects,and according to the severity,28 cases of gradeⅠ -Ⅱ,22 cases of grade Ⅲ -Ⅳ.50 COPD patients with acute phase of disease were selected as disease control group.50 healthy people were selected as healthy control group.The forced vital capacity (FVC),forced expiratory volume in first second (FEV1 ),FEV1 /FVC,peak oxygen uptake (peak VO2 ),peak oxygen uptake of expected value (peak VO2% Mr Pred),oxygen uptake efficiency slope (OUES),oxygen uptake efficiency platform (OUEP),when the anaerobic threshold (OUE @ AT)such as index,and the oxygen uptake efficiency and movement endurance were detected and analyzed.Results FVC,FEV1 ,FEV1 /FVC index values of COPD group were less than those of the control group,the differences were statistically significant (all P <0.05),and COPD patients with acute phase of FVC(2.86 ±0.36)L,FEV1 (1.25 ±0.36)L,FEV1 /FVC(50.16 ±5.37)% index values were less than COPD stabilization [(3.12 ±0.46)L,(1.51 ±0.38)L,(60.16 ±6.16)%)],the differences were statistically significant (all P <0.05).The peak VO2 ,peak VO2% Mr Pred,OUES,OUEP,OUE @ AT index values of COPD group were less than those of the control group,the differences were statistically significant (all P <0.05),and COPD patients with acute phase of peak VO2 (1 072.35 ±271.21)mL/min,peak VO2%pred(62.79 ±6.31),OUES(1.59 ±0.29),OUEP (25.72 ±3.42),OUE@AT(26.75 ±3.12)index values were less than patients with COPD stabilization[(1190.67 ± 286.21)mL/min,(70.76 ±6.27),(1.89 ±0.31 ),(31.46 ±4.05 ),(31.62 ±3.16)],the differences were statistically significant (all P <0.05).As the stabilization of disease severity in patients with COPD was aggravated, peak,VO2 peak VO2% Mr Pred,OUES,OUEP,OUE @ AT declined (1 089.62 ±221.68)mL/min vs.(1236.75 ± 235.37)mL/min,(67.28 ±5.03)vs.(75.81 ±5.39),(1.62 ±0.18)vs.(2.04 ±0.25),(30.67 ±6.47)vs. (34.17 ±4.40),(30.31 ±3.42)vs.(36.59 ±3.63)(F =16.92,12.71,4.27,8.75,7.59,P <0.05).Patients with COPD stabilization OUES,OUEP,OUE @ AT peak oxygen uptake efficiency indexes and movement endurance targets were positively correlated with VO2% Mr Pred (r =0.451,0.462,0.451,P =0.019,0.012,0.26),there was a positive correlation with peak VO2 (r =0.446,0.452,0.446,P =0.023,0.011,0.29).Conclusion COPD patients oxygen uptake efficiency and movement endurance than healthy people,patients with COPD oxygen uptake efficiency and movement endurance is associated with illness and severity of COPD,and COPD patients exercise endurance on the oxygen uptake efficiency also has a certain degree of influence.