ABSTRACT
@#Objective To explore the value of the three auxiliary examinations of transcranial ultrasound imaging,magnetic sensitivity weighted imaging,and magnetic resonance imaging in the identification of progressive supranuclear palsy and Parkinson’s disease.Methods Twenty-two clinically diagnosed patients with PSP,33 patients with PD were selected,and 30 cases in the control group underwent TCS,SWI,and MRI examinations and medical records were comprehensive.ROC curve was used to compare and analyze the results of TCS,SWI and MRI.The value of three auxiliary examinations in the identification of progressive supranuclear palsy and Parkinson’s disease was discussed.Results Compared with the PD group and the control group,the ratio of hyperechoic lenticular nucleus,the ratio of the minimum diameter of the third ventricle more than 10mm,the midbrain area/pontine area,the ratio of midbrain/pontine diameter,magnetic resonance Parkinson’s index,low signal strength of the putamen,and low signal strength of the red nucleus in the PSP group were higher (P<0.01).Compared with the PSP group and the control group,the substantia nigra hyperechoic area,the ratio of total substantia nigra hyperechoic area to total midbrain area in the PD group were higher (P<0.01).According to the ROC curve,it can be observed that the sensitivity of substantia nigra hyperechoic area in TCS was high while the specificity of low signal intensity of putamen in SWI was high as well;When TCS and SWI jointly identified the PD group and PSP group,the sensitivity was 93.9%,the specificity was 81.8%,the area under the curve (AUC) was 0.938,and the value of identification diagnosis was high.The sensitivity and specificity of the MRPI and P/M values in the identification of the PSP group and PD group reached 100%.Conclusion The value of TCS,SWI,and MRI in the identification of PSP and PD is different.TCS combined with SWI is of higher diagnosis value in the identification of PD group and PSP group,which provides a new method for the identification diagnosis of PSP.The overall value of differential diagnosis of MRI is better than TCS and SWI.