The mediation of immune activation on serotonin and glutamate systems in pathological process of depression / 中国药理学通报

Immunological alterations and changes in neurotransmission are considered to be crucial in the pathological process of depression. An immune activation including increased production of proinflammatory cytokines has repeatedly been described in depression, which shines a clue for new anti-depression therapy. Immune activation will lead to depression through serotonin and glutamate systems. This paper is attempted to review the immune mediated alterations on serotonin and glutamate systems.

Progress of receptors mechanism on depression / 中国药理学通报

Early study have been proved that Monoaminergic receptor are playing an important role in the progress of depression.At present,other receptors have been discovered which involved in the pathogenesis and treatment of depression.This paper is attempted to review the new progress of investigation into glutamate receptors,corticotropin-releasing factor receptors,neurokinin receptors and adrenocorticosteroid receptors related with depression mechanism respectively.