1.
International Journal of Traditional Chinese Medicine
;
(6): 245-246, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-399534
ABSTRACT
Objective To investigate the protective funcfon of total saponin of Radix Dipsaci of Sichuan on cerebral ischemia.Methods 40 rats were randomly divided into a nonllal group,a model group,a low-dose total saponin(10 blocking middle cerebral artery with interpolation method.Brain homogenate was extracted,and superoxide dismutase(SOD),glutathione peroxidase(GSH-Px),and malondialdehyde(MDA)in the brain homogenate were measured.Results In the low-dose and high-dose total saponin groups.the infarction area of cerebral ischcmia and the content of MDA were significantly reduced and the activity of SOD and GSH-Px were increased.Conclusion Total saponin of Radix Dipsaci of Sichuan has obvious protective function on focal cerebral ischemia.