ABSTRACT
Objective We aimed to evaluatd the effect of oral nursing with oral washing on patients with peroral endotracheal intubation and discuss the appropriate oral nursing method for patients with patients with peroral endotracheal intubation. Methods We chose 150 patients with indwelling peroral endotracheal intubation after neurosurgery and divided them into the control group (73 cases) and the test group (77 cases). The test group received oral nursing with oral washing while the control group with routine oral nursing method. We compared the incidence of halitosis, the moist degree of oral cavity and the amount of the tooth fungus spot between the two groups. Results The incidence of halitosis and the amount of the tooth fungus spot in the test group were lower than those of the control group; The moist degree of oral cavity in the test group was higher than that of the control group, P<0.01. Conclusions Oral washing could effectively control halitosis, keep oral cavity moist and prevent the formation of tooth fungus spot.
ABSTRACT
Objective: To investigate the biological function of soybean selenoprotein by the study of anti-oxidation,immunological and anticarcinogenic efficacy. Method: The soybean selenoprotein at different doses of Se were fed intra-gastrically in Kunming mice. A low Se feedstuff was used as basic diet. Result: (1) when dose is below 202.5 ?g/kg bw Se, the number of white cell and red cell was increased remarkably, and the activity of GSH-Px and SOD in liver and serum was increased at dose dependent manner, but LPO in serum and liver was decreased noticeably. At level of 607.5?g/kg, all the indices were reversed; (2) A dose-dependent cancer protective effect was expressed in range of 22.5-202.5?g/kg Se of soybean selemoprotein in the diet. Feeding soybean selenoprotein can postpone the death of mice with carcinoma . Total tumour yield was consistently reduced by 78% with 202.5?g/kg supplementation; (3) Any abnormal response was never noticed during all trial by supplementing 202.5?g/kg selenoprotein. Conclusion: The increased effect of anti-oxidation and immunological modulation might be the mechanism of tumour suppression by soybean selenoprotein, and Kunming mice tolerated the soybean selenoprotein very well without any side effects.